Microdialysis sampling system is a technique for dynamic micro biochemical sampling from living organisms, characterized by continuous sampling, dynamic observation, quantitative analysis, small sampling volume, and minimal tissue damage.

It mainly consists of a microinjection pump, a awake activity device, a microdialysis probe, and an automatic collector.

This system has been increasingly widely used in fields such as neuroscience and pharmaceutical research.

The main principle of the microdialysis sampling system is to place a probe with a semi permeable membrane in specific tissues of experimental animals, and use a pump to push the solution to the probe, so that the target substance in the tissue diffuses into the probe through the semi permeable membrane, in order to extract the low molecular weight substance to be measured from the tissue for further analysis. This equipment can perform continuous perfusion experiments on anesthetized or awake animals, providing a new technology for the development of fields such as medicine, pharmacy, and life sciences.

Application areas: psychopharmacology, neuropathology and cancer research, pharmacokinetics and toxicology, physiological pharmacology, analysis of biogenic amines, analysis of acetylcholine/choline, analysis of free radicals/amino acids, various tissue biochemistry/drug analysis.

working principle:

A complete brain microdialysis system consists of the following parts:

Microdialysis pump

The high stability and accuracy of microdialysis pumps, which are used to continuously provide perfusion fluid, are beneficial for the conduct of dialysis experiments.

microdialysis probe

Sober animal lifemobilizer

Dialysis probe accessories：
Liquid switch, probe holder, pipeline, connector, etc., play a role in guiding, positioning, fixing, etc

Microdialysis fluid collector

Cooperate with the microdialysis collection system to collect and store microdialysis samples at low temperatures.

Microdialysis sample collector, used for low-temperature storage of samples. The instrument has 20 sample grades and can collect 20 samples continuously in single probe mode or 2 × 10 samples continuously in dual probe mode. The minimum sample size that can be collected is 1ul. The storage temperature is 8 ℃

The cooling micro collector can simultaneously collect 1-2 dialysate, and with the help of a dual channel microdialysis pump, it can perform 2-channel microdialysis sampling experiments simultaneously;

Minimum cooling temperature: 8 ℃;

Number of collected samples: 64（

Wide screen LCD display with 4X20 characters, RS232 and USB connection;

reference:

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